Hodgkin lymphoma in a patient with chronic lymphocytic leukaemia--a rare presentation of Richter's transformation.
نویسندگان
چکیده
Richter's transformation of chronic lymphocytic leukaemia (CLL) to high-grade B-cell Non-Hodgkin lymphoma occurs in < 5% of CLL cases. Transformation of CLL to Hodgkin Lymphoma is a much rarer event and here we describe a patient who developed Richter's transformation into a Hodgkin Lymphoma presenting as rapidly progressive hepatosplenomegaly.
منابع مشابه
Intravascular large B‐cell lymphoma presenting as Richter's syndrome with cerebral involvement in a patient with chronic lymphocytic leukemia
Intravascular large B-cell lymphoma (IVLBCL) is an aggressive non-Hodgkin's lymphoma which can present with B symptoms, rash, and neurological deterioration. Up to 10% of cases of IVLBCL are associated with other hematological neoplasms, including this extremely rare presentation of IVLBCL as Richter's transformation in chronic lymphocytic leukemia.
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In 1928, a pathologist at Bellevue Hospital in New York City named Maurice Richter performed an autopsy on a 46-year-old man. The patient had a 2-month history of abdominal pain and weight loss and was admitted to the hospital, where he died. He was found to have lymphatic leukemia and reticulum cell sarcoma.[1] In 1964, the term “Richter's syndrome” (or “Richter's transformation”) was introduc...
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ورودعنوان ژورنال:
- Irish medical journal
دوره 108 4 شماره
صفحات -
تاریخ انتشار 2015